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Article

A polymorphism in the inducible nitric oxide synthase gene is associated with tuberculosis.

Tuberculosis (Edinburgh, Scotland) - 1 Jul 2007

Gómez Luis Miguel, Anaya Juan-Manuel, Vilchez José Ramón, Cadena Jose, Hinojosa Rosa, Vélez Luciano, Lopez-Nevot Miguel Angel, Martín Javier

Abstract excerpt

iNOS or NOS2 is a molecule that plays a key role in the immunological control of a broad spectrum of infectious agents. Investigation is hampered by difficulty in estimating in vivo production of nitric oxide (NO), but genetic studies provide a potential means of examining the relation between NO production and disease outcome. To better characterize the host genetic factors determining the susceptibility to TB,...

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Identifiers

PMID: 17475563
DOI: 10.1016/j.tube.2007.03.002

Genes

TST
NOS2

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