Article
The inducible nitric oxide synthase promoter polymorphism does not confer susceptibility to systemic lupus erythematosus.
Rheumatology (Oxford, England) - 1 Jan 2003
López-Nevot M A, Ramal L, Jiménez-Alonso J, Martín J
Abstract excerpt
OBJECTIVE: There is increasing evidence that nitric oxide (NO) may be important in the pathogenesis of systemic lupus erythematosus (SLE). One possible explanation for the differences observed in NO production between SLE patients and controls is variation in the 5' promoter region of the NOS2 gene, which controls NOS2 transcription. We studied the possible contribution of (CCTTT)(n) microsatellite polymorphism...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
