Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

NQO2 gene is associated with clozapine-induced agranulocytosis.

Tissue antigens - 1 Dec 2003

Ostrousky O, Meged S, Loewenthal R, Valevski A, Weizman A, Carp H, Gazit E

Abstract excerpt

Clozapine is a dibenzodiazepine neuroleptic with atypical pharmacological and clinical profiles. Treatment with this drug may be complicated with agranulocytosis (AGR). It is likely that defective oxidative mechanism may be the cause of AGR. A candidate gene, dihydronicotinamide riboside (NRH) qu...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bipolar Disorder and Treatment
Share to Clozapine
Share to Densitometry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genotype

Share to Polymorphism, Single-Stranded Conformational

Share to Promoter Regions, Genetic

Share to Quinone Reductases

Source

Identifiers

PMID: 14617031
DOI: 10.1046/j.1399-0039.2003.00133.x

Genes

NQO2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-14617031-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

NQO2 gene is associated with clozapine-induced agranulocytosis.PMID 14617031Read ↗

Genetic risk factors for clozapine-induced neutropenia and agranulocytosis in a Dutch psychiatric population.Semantic proximity Read ↗

Clozapine-induced agranulocytosis and its genetic determinants.Semantic proximity Read ↗

Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropeniaSemantic proximity Read ↗

Pharmacogenomics of Clozapine-induced agranulocytosis: a systematic review and meta-analysis.Semantic proximity Read ↗

Clozapine Pharmacogenetic Studies in Schizophrenia: Efficacy and AgranulocytosisSemantic proximity Read ↗

Candidate gene analysis identifies a polymorphism in HLA-DQB1 associated with clozapine-induced agranulocytosis.Semantic proximity Read ↗

[Clozapine-induced agranulocytosis: genetic risk factors and an immunologic explanatory model].Semantic proximity Read ↗

Clozapine-induced agranulocytosis and hereditary polymorphisms of clozapine metabolizing enzymes: no association with myeloperoxidase and cytochrome P4502D6.Semantic proximity Read ↗

Further evidence of human leukocyte antigen-encoded susceptibility to clozapine-induced agranulocytosis independent of ancestry.Semantic proximity Read ↗

Relation of the Allelic Variants of Multidrug Resistance Gene to Agranulocytosis Associated With Clozapine.Semantic proximity Read ↗

Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.Semantic proximity Read ↗

Establishing the characteristics of an effective pharmacogenetic test for clozapine-induced agranulocytosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.