Article
Cytochrome P450 and manganese superoxide dismutase genes polymorphisms in systemic lupus erythematosus.
Immunology letters - 15 Nov 2003
Yen Jeng-Hsien, Chen Chung-Jen, Tsai Wen-Chun, Lin Chia-Hui, Ou Tsan-Teng, Hu Chaur-Jong, Liu Hong-Wen
Abstract excerpt
OBJECTIVES: To investigate the role of cytochrome P450 1A1 (CYP1A1) and manganese superoxide dismutase (Mn SOD) genes polymorphisms in the pathogenesis of systemic lupus erythematosus (SLE) in Taiwan. METHODS: CYP1A1 and Mn SOD genes polymorphisms were determined by the polymerase chain reaction/restriction fragment length polymorphism (RFLP) method in 90 patients with SLE and 94 healthy controls. RESULTS: The...
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