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Article

Genetic polymorphism of drug metabolism enzymes (GSTM1, GSTT1 and GSTP1) in the healthy Malian population.

Molecular biology reports - 1 Jan 2020

Kassogue Yaya, Diakite Brehima, Kassogue Oumar, Konate Issa, Tamboura Kadidiatou, Diarra Zoumana, Dehbi Hind, Nadifi Sellama, Traore Cheick Bougadari, Dao Sounkalo, Doumbia Seydou, Dolo Guimogo

Abstract excerpt

Glutathione S-transferase genes, known to be highly polymorphic, are implicated in the process of phase II metabolism of many substrates, including xenobiotics, anticancer and anti-infective drugs. The detoxification activity is linked to individual genetic makeup. Therefore, the identification of alleles and genotypes in these genes within a population may help to better design genetic susceptibility and...

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PMID: 31650384
DOI: 10.1007/s11033-019-05143-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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