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Article

Association between combinations of glutathione-S-transferase M1, T1 and P1 genotypes and non-alcoholic fatty liver disease.

Liver international : official journal of the International Association for the Study of the Liver - 1 Feb 2009

Hori Masaharu, Oniki Kentaro, Nakagawa Takehiro, Takata Keiji, Mihara Shuichi, Marubayashi Toru, Nakagawa Kazuko

Abstract excerpt

BACKGROUND/AIMS: Glutathione-S-transferases (GSTs) play a crucial role in antioxidant defence mechanisms, by detoxifying xenobiotics and by inactivating endogenous byproducts of oxidative stress. Functional failure, as a sequel of an altered GST genotype, may thus aggravate non-alcoholic fatty liver disease (NAFLD). This study investigated whether the GSTs genotypes could affect the risk for NAFLD. METHODS: A...

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Source

Identifiers

PMID: 18492019
DOI: 10.1111/j.1478-3231.2008.01794.x

Genes

GSTM1
GSTT1
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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