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Article

GSTT1 and GSTM1 null genotypes may facilitate hepatitis C virus infection becoming chronic.

The Journal of infectious diseases - 1 May 2007

Martínez Carmen, García-Martín Elena, Ladero José M, Herráez Oscar, Ortega Luis, Taxonera Carlos, Suárez Avelina, Díaz-Rubio Manuel, Agúndez José A G

Abstract excerpt

Oxidative stress contributes to hepatitis C virus (HCV)-induced liver damage. The activity of antioxidant glutathione S-transferases (GSTs) T1 and M1 is polymorphic. The GSTT1 and GSTM1 genotypes were identified in 139 HCV-infected patients and in 329 healthy individuals. Among patients, there was an excess of GSTT1 (odds ratio [OR], 2.76 [95% confidence interval [CI], 1.77-4.30]; P<.001) and GSTM1 (OR, 1.54 [95%...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17397002
DOI: 10.1086/513569

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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GSTT1 and GSTM1 null genotypes may facilitate hepatitis C virus infection becoming chronic.PMID 17397002Read ↗

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