Article
GSTT1 and GSTM1 null genotypes may facilitate hepatitis C virus infection becoming chronic.
The Journal of infectious diseases - 1 May 2007
Martínez Carmen, García-Martín Elena, Ladero José M, Herráez Oscar, Ortega Luis, Taxonera Carlos, Suárez Avelina, Díaz-Rubio Manuel, Agúndez José A G
Abstract excerpt
Oxidative stress contributes to hepatitis C virus (HCV)-induced liver damage. The activity of antioxidant glutathione S-transferases (GSTs) T1 and M1 is polymorphic. The GSTT1 and GSTM1 genotypes were identified in 139 HCV-infected patients and in 329 healthy individuals. Among patients, there wa...
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