Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Monocytes differentiated into macrophages and dendritic cells in the presence of human IFN-λ3 or IFN-λ4 show distinct phenotypes.

Journal of leukocyte biology - 1 Aug 2021

De Manjarika, Bhushan Anand, Chinnaswamy Sreedhar

Abstract excerpt

Human IFN-λ4 is expressed by only a subset of individuals who possess the ΔG variant allele at the dinucleotide polymorphism rs368234815. Recent genetic studies have shown an association between rs368234815 and different infectious and inflammatory disorders. It is not known if IFN-λ4 has immunomodulatory activity. The expression of another type III IFN, IFN-λ3, is also controlled by genetic polymorphisms that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytokines

Share to Dendritic Cells

Share to Immunomodulation

Share to Immunophenotyping

Share to Interferon-gamma

Share to Macrophage Activation

Share to Macrophages

Share to Monocytes

Source

Open in PubMed Open full text

Identifiers

PMID: 33205487
DOI: 10.1002/JLB.3A0120-001RRR
PMCID: PMC7611425

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Monocytes differentiated into macrophages and dendritic cells in the presence of human IFN-λ3 or IFN-λ4 show distinct phenotypes.PMID 33205487Read ↗

Distinct molecular phenotypes involving several human diseases are induced by IFN-λ3 and IFN-λ4 in monocyte-derived macrophages.Semantic proximity Read ↗

IFN-γ Drives Human Monocyte Differentiation into Highly Proinflammatory Macrophages That Resemble a Phenotype Relevant to Psoriasis.Semantic proximity Read ↗

Interferon-Beta Induces Distinct Gene Expression Response Patterns in Human Monocytes versus T cellsSemantic proximity Read ↗

Expression profiles of human interferon‐alpha and interferon‐lambda subtypes are ligand‐ and cell‐dependentSemantic proximity Read ↗

Analysis of interferon-λ1 gene activation and functionSemantic proximity Read ↗

IL-34 induces the differentiation of human monocytes into immunosuppressive macrophages. antagonistic effects of GM-CSF and IFNγ.Semantic proximity Read ↗

IFN-α regulates Blimp-1 expression via miR-23a and miR-125b in both monocytes-derived DC and pDC.Semantic proximity Read ↗

Effects of temporal IFNγ exposure on macrophage phenotype and secretory profile: exploring GMP-Compliant production of a novel subtype of regulatory macrophages (MregIFNγ0) for potential cell therapeutic applications.Semantic proximity Read ↗

MAP kinase p38<i>α</i> regulates type III interferon (<i>IFN-</i>λ<i>1</i>) gene expression in human monocyte-derived dendritic cells in response to RNA stimulationSemantic proximity Read ↗

Identification of Differentially Expressed Long Non-coding RNAs in Polarized Macrophages.Semantic proximity Read ↗

The impact of the interferon-lambda family on the innate and adaptive immune response to viral infectionsSemantic proximity Read ↗

Differential Responses to IFN-α Subtypes in Human T Cells and Dendritic CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.