Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cloning and mutation analysis of ZFP276 as a candidate tumor suppressor in breast cancer.

Journal of human genetics - 1 Jan 2003

Wong Jasmine C Y, Gokgoz Nalan, Alon Noa, Andrulis Irene L, Buchwald Manuel

Abstract excerpt

Loss of heterozygosity (LOH) involving chromosome 16q23.4 occurs frequently in breast tumors, which suggests that this region may contain a tumor suppressor gene. Since ZFP276 is located in this region, we have therefore cloned and performed mutation analysis of its coding region in 70 breast tumors. One silent polymorphism and two alterations predicted to result in amino acid changes were detected. Absence of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blotting, Northern
Share to Chromosomes, Human, Pair 16

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA, Complementary

Share to Genes, Tumor Suppressor

Share to Polymorphism, Single-Stranded Conformational

Share to Sequence Homology, Amino Acid

Share to Tumor Suppressor Proteins

Share to Zinc Fingers

Source

Identifiers

PMID: 14605947
DOI: 10.1007/s10038-003-0088-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Cloning and mutation analysis of ZFP276 as a candidate tumor suppressor in breast cancer.PMID 14605947Read ↗

Loss, mutation and deregulation of L3MBTL4 in breast cancers.Semantic proximity Read ↗

Alteration of WWOX in human cancer: a clinical view.Semantic proximity Read ↗

A possible tumor suppressor role of the KLF5 transcription factor in human breast cancer.Semantic proximity Read ↗

Genetic alterations of the WWOX gene in breast cancer.Semantic proximity Read ↗

Sequencing, transcript identification, and quantitative gene expression profiling in the breast cancer loss of heterozygosity region 16q24.3 reveal three potential tumor-suppressor genes.Semantic proximity Read ↗

Analysis of a 69-kb contiguous genomic sequence at a putative tumor suppressor gene locus on human chromosome 6q27.Semantic proximity Read ↗

ATBF1 and NQO1 as candidate targets for allelic loss at chromosome arm 16q in breast cancer: absence of somatic ATBF1 mutations and no role for the C609T NQO1 polymorphism.Semantic proximity Read ↗

Evidence for a gene on 17p13.3, distal to TP53, as a target for allele loss in breast tumors without p53 mutations.Semantic proximity Read ↗

Identification of rare variants in the hLIMD1 gene in breast cancer.Semantic proximity Read ↗

Genetic alterations of the tumor suppressor gene WWOX in esophageal squamous cell carcinoma.Semantic proximity Read ↗

Identification of homozygous deletions at chromosome 16q23 in aflatoxin B1 exposed hepatocellular carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.