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Article

Immunophenotypic features of acute myeloid leukaemia patients exhibiting high FLT3 expression not associated with mutations.

British journal of haematology - 1 Apr 2011

Riccioni Roberta, Pelosi Elvira, Riti Viviana, Castelli Germana, Lo-Coco Francesco, Testa Ugo

Abstract excerpt

FMS-related tyrosine kinase 3 (FLT3) mutations are found in 30% of cases of acute myeloid leukaemia (AML). In addition, recent studies have lead to the identification of about 10-15% of AML patients displaying high expression of FLT3, not associated with mutations of the receptor (FLT3 Wild-type High, FLT3WTH). These AMLs, as well as those displaying internal tandem duplication (ITD) are associated with an...

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Share to Antigens, CD34
Share to fms-Like Tyrosine Kinase 3

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunophenotyping

Share to Leukemia, Myeloid, Acute

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Share to Receptor, TIE-2

Share to Receptors, TNF-Related Apoptosis-Inducing Ligand

Share to Vascular Endothelial Growth Factor Receptor-2

Source

Identifiers

PMID: 21332708
DOI: 10.1111/j.1365-2141.2011.08577.x

Genes

FLT3

Provenance

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