Article
Analysis of chromosomal imbalances in de novo CD5-positive diffuse large-B-cell lymphoma detected by comparative genomic hybridization.
Genes, chromosomes & cancer - 1 Jan 2004
Karnan Sivasundaram, Tagawa Hiroyuki, Suzuki Ritsuro, Suguro Miyuki, Yamaguchi Motoko, Okamoto Masataka, Morishima Yasuo, Nakamura Shigeo, Seto Masao
Abstract excerpt
We recently demonstrated that the prognosis for de novo CD5-positive (CD5+) diffuse large-B-cell lymphoma (DLBCL) is markedly worse than that for CD5-negative (CD5-) DLBCL. Our findings also suggested that on the basis of its clinical features CD5+ DLBCL may constitute a unique disease category. However, the genetic basis for these two categories has not been established. Therefore, we performed comparative...
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