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Genome-Wide Array-Based Comparative Genomic Hybridization of Diffuse Large B-Cell Lymphoma

1 Sept 2004

Abstract excerpt

Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin's lymphoma and exhibits aggressive and heterogeneous clinical behavior. To genetically characterize DLBCL, we established our own array-based comparative genomic hybridization and analyzed a total of 70 cases [26 CD-positive (CD5+) DLBCL and 44 CD5-negative (CD5-) DLBCL cases]. Regions of genomic aberrations observed in >20% of cases of...

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PMID: 15342373
DOI: 10.1158/0008-5472.can-03-4056

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