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Article

Amplification of 2p as a genomic marker for transformation in lymphoma

15 May 2014

Abstract excerpt

To outline further genetic mechanisms of transformation from follicular lymphoma (FL) to diffuse large B-cell lymphoma (DLBCL), we have performed whole genome array-CGH in 81 tumors from 60 patients [29 de novo DLBCL (dnDLBCL), 31 transformed DLBCL (tDLBCL), and 21 antecedent FL]. In 15 patients, paired tumor samples (primary FL and a subsequent tDLBCL) were available, among which three possessed more than two...

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PMID: 24832791
DOI: 10.1002/gcc.22184

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