Article
De novo CD5+ diffuse large B-cell lymphomas express VH genes with somatic mutation.
Blood - 15 Feb 1998
Taniguchi M, Oka K, Hiasa A, Yamaguchi M, Ohno T, Kita K, Shiku H
Abstract excerpt
To clarify the cellular origin of de novo CD5+ diffuse large B-cell lymphoma (CD5+ DLBL), particularly in comparison with other CD5+ B-cell neoplasms such as chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL), we analyzed the nucleotide sequence of the Ig heavy chain variable regio...
Topics
- Aged
- Aged, 80 and over
- Amino Acid Sequence
- Base Sequence
- CD5 Antigens
- Female
- Genes, Immunoglobulin
- Humans
- Immunoglobulin Heavy Chains
- Immunoglobulin Variable Region
- Lymphoma, B-Cell
- Lymphoma, Large B-Cell, Diffuse
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
