Article
Involvement of zebrafish Na+,K+ ATPase in myocardial cell junction maintenance.
The Journal of cell biology - 15 Jan 2007
Cibrián-Uhalte Elena, Langenbacher Adam, Shu Xiaodong, Chen Jau-Nian, Abdelilah-Seyfried Salim
Abstract excerpt
Na(+),K(+) ATPase is an essential ion pump involved in regulating ionic concentrations within epithelial cells. The zebrafish heart and mind (had) mutation, which disrupts the alpha1B1 subunit of Na(+),K(+) ATPase, causes heart tube elongation defects and other developmental abnormalities that are reminiscent of several epithelial cell polarity mutants, including nagie oko (nok). We demonstrate genetic...
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