Article

scRNA-seq reveals the diversity of the developing cardiac cell lineage and molecular building blocks of the primary pacemaker

2023-06-27

Abstract excerpt

The heart is comprised of a variety of specialized cell types that work in unison to maintain blood flow. Here we utilized scRNA-seq analysis to delineate the diversity of cardiac cell types in the zebrafish. With the growing use of the zebrafish to model human heart biology, a deeper insight into its complex cellular composition is critical for a better understanding of heart function, development, and associated...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 68372d20-3820-544b-8fb7-4bc8d39a3ea4
DOI: 10.1101/2023.06.26.546508

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

scRNA-seq reveals the diversity of the developing cardiac cell lineage and molecular building blocks of the primary pacemakerDOI 10.1101/2023.06.26.546508Read

An organ-wide spatiotemporal transcriptomic and cellular atlas of the regenerating zebrafish heartSemantic proximity Read

Transcriptome Profile of the Sinoatrial Ring Reveals Conserved and Novel Genetic Programs of the Zebrafish PacemakerSemantic proximity Read

Transcriptome profile of the sinoatrial ring reveals conserved and novel genetic programs of the zebrafish pacemakerSemantic proximity Read

Non-cardiomyocytes in the heart in embryo development, health, and disease, a single-cell perspectiveSemantic proximity Read

A human developing heart atlas reveals cardiovascular cell diversity for in vitro model benchmarkingSemantic proximity Read

Conservation and divergence of transcriptional heterogeneity in the cardiac conduction systemSemantic proximity Read

Multi-chamber cardioids unravel human heart development and cardiac defectsSemantic proximity Read

uniHEART: An Ensemble Atlas of Cardiac Cells Provides Multifaceted Portraits of the Human HeartSemantic proximity Read

The single-cell atlas of the heart reveals an unexpected erythrocyte-like cardiomyocyteSemantic proximity Read

Multi-chamber cardioids unravel human heart development and cardiac defectsSemantic proximity Read

Zebrafish as a Versatile Model for Cardiovascular Research: Peering into the Heart of the MatterSemantic proximity Read

Transcriptome analysis of mouse and human sinoatrial node cells reveals a conserved genetic programSemantic proximity Read