Article
MDR1 genetic polymorphism does not modify either cell permissiveness to HIV-1 or disease progression before treatment.
The Journal of infectious diseases - 15 Feb 2004
Bleiber Gabriela, May Margaret, Suarez Carlos, Martinez Raquel, Marzolini Catia, Egger Matthias, Telenti Amalio
Abstract excerpt
Nonphysiological overexpression of the ABC transporter P-glycoprotein (P-gp), which is encoded by MDR1, has been associated with reduced susceptibility to human immunodeficiency virus (HIV) type 1 infection in vitro. We analyzed (1) the expression and genotype of MDR1 and their relationship to HI...
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