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Article

MDR1 genetic polymorphism does not modify either cell permissiveness to HIV-1 or disease progression before treatment.

The Journal of infectious diseases - 15 Feb 2004

Bleiber Gabriela, May Margaret, Suarez Carlos, Martinez Raquel, Marzolini Catia, Egger Matthias, Telenti Amalio

Abstract excerpt

Nonphysiological overexpression of the ABC transporter P-glycoprotein (P-gp), which is encoded by MDR1, has been associated with reduced susceptibility to human immunodeficiency virus (HIV) type 1 infection in vitro. We analyzed (1) the expression and genotype of MDR1 and their relationship to HIV-1 permissiveness of CD4+ T cells from 128 healthy blood donors and (2) the role that alleles of MDR1 exons 21 and 26...

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Identifiers

PMID: 14767809
DOI: 10.1086/380134

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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