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Article

Characterization of cis-elements mediating the stimulation of glucose-6-phosphate transporter promoter activity by glucocorticoids.

Gene - 27 Nov 2003

Kallwellis-Opara Angela, Zaho Xiangshan, Zimmermann Uwe, Unterman Terry G, Walther Reinhard, Schmoll Dieter

Abstract excerpt

The endoplasmatic glucose-6-phosphate transporter is involved in the control of hepatic glucose production and blood glucose homeostasis. In this study, the expression of a luciferase reporter gene under the control of the glucose-6-phosphate transporter gene promoter was examined in transiently transfected hepatoma cells. The promoter activity was stimulated approximately 2.5-fold by dexamethasone. Mutational...

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PMID: 14597389
DOI: 10.1016/s0378-1119(03)00810-2

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