Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Glucose-6-Phosphatase Catalytic Subunit Gene Promoter Contains Both Positive and Negative Glucocorticoid Response Elements

22 Jul 2005

Abstract excerpt

Glucose-6-phosphatase catalyzes the final step in the gluconeogenic and glycogenolytic pathways. Glucocorticoids stimulate glucose-6-phosphatase catalytic subunit (G6Pase) gene transcription and studies performed in H4IIE hepatoma cells demonstrate the presence of a glucocorticoid response unit (GRU) in the proximal G6Pase promoter. In vitro deoxyribonuclease I footprinting analyses show that the glucocorticoid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetics and Neurodevelopmental Disorders
Share to Glycogen Storage Diseases and Myoclonus
Share to Pancreatic function and diabetes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16037130
DOI: 10.1210/me.2004-0497

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Glucose-6-Phosphatase Catalytic Subunit Gene Promoter Contains Both Positive and Negative Glucocorticoid Response ElementsPMID 16037130Read ↗

Multiple Promoters Exist in the Human GR Gene, One of Which Is Activated by GlucocorticoidsSemantic proximity Read ↗

Multiple Promoters Exist in the Human GR Gene, One of Which Is Activated by GlucocorticoidsSemantic proximity Read ↗

A Multicomponent Insulin Response Sequence Mediates a Strong Repression of Mouse Glucose-6-phosphatase Gene Transcription by InsulinSemantic proximity Read ↗

Multifaceted Control of GR Signaling and Its Impact on Hepatic Transcriptional Networks and MetabolismSemantic proximity Read ↗

Characterization of cis-elements mediating the stimulation of glucose-6-phosphate transporter promoter activity by glucocorticoids.Semantic proximity Read ↗

Insulin and epidermal growth factor suppress basal glucose-6-phosphatase catalytic subunit gene transcription through overlapping but distinct mechanisms.Semantic proximity Read ↗

Signal-dependent control of gluconeogenic key enzyme genes through coactivator-associated arginine methyltransferase 1.Semantic proximity Read ↗

Regulation of Hepatic Gluconeogenesis by an ER-Bound Transcription Factor, CREBHSemantic proximity Read ↗

Glucocorticoid Receptor‐Binding and Transcriptome Signature in CardiomyocytesSemantic proximity Read ↗

Sequence variation between the mouse and human glucose-6-phosphatase catalytic subunit gene promoters results in differential activation by peroxisome proliferator activated receptor gamma coactivator-1alpha.Semantic proximity Read ↗

Mutation/polymorphism scanning of glucose-6-phosphatase gene promoter in noninsulin-dependent diabetes mellitus patients.Semantic proximity Read ↗

Protein kinase A phosphorylates hepatocyte nuclear factor-6 and stimulates glucose-6-phosphatase catalytic subunit gene transcription.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.