Article
Identification of a glucocorticoid response element in the rat beta2-adrenergic receptor gene.
Molecular pharmacology - 1 Dec 1998
Cornett L E, Hiller F C, Jacobi S E, Cao W, McGraw D W
Abstract excerpt
Regulation of beta2-adrenergic receptor (beta2AR) levels by glucocorticoids is a physiologically important mechanism for altering beta2AR responsiveness. Glucocorticoids increase beta2AR density by increasing the rate of beta2AR gene transcription, but the cis-elements involved have not been well...
Topics
- Animals
- Cells, Cultured
- Glucocorticoids
- Luciferases
- Mutation
- Plasmids
- Promoter Regions, Genetic
- Rats
- Receptors, Adrenergic, beta
- Receptors, Glucocorticoid
- Response Elements
- Transcription Factors
