Mouse Chromosome 17A3.3 Contains 13 Genes That Encode Functional Tryptic-like Serine Proteases with Distinct Tissue and Cell Expression Patterns

Abstract excerpt

Probing of the mouse EST data base at GenBank trade mark with known tryptase cDNAs resulted in the identification of undiscovered serine protease transcripts whose genes reside at a 1.5-Mb complex on mouse chromosome 17A3.3. Mouse tryptase-5 (mT5), tryptase-6 (mT6), and mast cell protease-11 (mMCP-11) are new members of this serine protease superfamily whose amino acid sequences are 36-54% identical to each other...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Chemical Synthesis and Analysis
• Share to Coagulation, Bradykinin, Polyphosphates, and Angioedema
• Share to Mast cells and histamine