Article
Characterization of Genes Encoding Known and Novel Human Mast Cell Tryptases on Chromosome 16p13.3
1 Feb 1999
Abstract excerpt
Tryptases are serine proteases implicated in asthma and are very highly expressed in human mast cells. They fall into two groups, alpha and beta. Although several related tryptase mRNAs are known, it is unclear which if any are transcripts of separate haploid genes. The studies described here investigated the nature and number of human tryptases and sought possibly novel members of the family. To this end, two...
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