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Article

Rapid lineage-specific diversification of the mast cell chymase locus during mammalian evolution.

Immunogenetics - 1 Aug 2006

Gallwitz Maike, Hellman Lars

Abstract excerpt

Serine proteases constitute the major protein granule content of cells of several hematopoietic cell lineages. A subgroup of these proteases, including the mast cell chymases, neutrophil cathepsin G, and T cell granzymes B to F and N, are in all investigated mammals encoded in one locus, the chymase locus. It is interesting to note that this locus has diversified greatly during the last 95 Myr of mammalian...

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Identifiers

PMID: 16807746
DOI: 10.1007/s00251-006-0123-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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