Article
Update of the human and mouse SERPIN gene superfamily.
Human genomics - 30 Oct 2013
Heit Claire, Jackson Brian C, McAndrews Monica, Wright Mathew W, Thompson David C, Silverman Gary A, Nebert Daniel W, Vasiliou Vasilis
Abstract excerpt
The serpin family comprises a structurally similar, yet functionally diverse, set of proteins. Named originally for their function as serine proteinase inhibitors, many of its members are not inhibitors but rather chaperones, involved in storage, transport, and other roles. Serpins are found in genomes of all kingdoms, with 36 human protein-coding genes and five pseudogenes. The mouse has 60 Serpin functional...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
