Article
Glucocorticoid-related genetic susceptibility for Alzheimer's disease.
Human molecular genetics - 1 Jan 2004
de Quervain Dominique J-F, Poirier Raphael, Wollmer M Axel, Grimaldi Luigi M E, Tsolaki Magdalini, Streffer Johannes R, Hock Christoph, Nitsch Roger M, Mohajeri M Hasan, Papassotiropoulos Andreas
Abstract excerpt
Because glucocorticoid excess increases neuronal vulnerability, genetic variations in the glucocorticoid system may be related to the risk for Alzheimer's disease (AD). We analyzed single-nucleotide polymorphisms in 10 glucocorticoid-related genes in a population of 814 AD patients and unrelated...
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