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Article

Insights into catalysis by a knotted TrmD tRNA methyltransferase.

Journal of molecular biology - 7 Nov 2003

Elkins Patricia A, Watts Joseph M, Zalacain Magdalena, van Thiel Adam, Vitazka Patrik R, Redlak Maria, Andraos-Selim Cecile, Rastinejad Fraydoon, Holmes Walter M

Abstract excerpt

The crystal structure of Escherichia coli tRNA (guanosine-1) methyltransferase (TrmD) complexed with S-adenosyl homocysteine (AdoHcy) has been determined at 2.5A resolution. TrmD, which methylates G37 of tRNAs containing the sequence G36pG37, is a homo-dimer. Each monomer consists of a C-terminal...

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PMID: 14583191
DOI: 10.1016/j.jmb.2003.09.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14583191-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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