Article
Cyclosporin A Suppresses Replication of Hepatitis C Virus Genome in Cultured Hepatocytes
23 Oct 2003
Abstract excerpt
Persistent infection of hepatitis C virus (HCV) is a major cause of liver diseases such as chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. Searching for a substance with anti-HCV potential, we examined the effects of a variety of compounds on HCV replication using a HCV subgenomic replicon cell culture system. Consequently, the immunosuppressant cyclosporin A (CsA) was found to have a...
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