Article
Molecular biology of hepatitis B virus e antigen.
Journal of gastroenterology and hepatology - 1 Oct 1997
Ou J H
Abstract excerpt
Hepatitis B virus (HBV) e antigen (HBeAg) was discovered in 1972 as one of the serological markers of HBV infection. Although 25 years have passed since its initial discovery, the function of this antigen in the life cycle of HBV has remained elusive. Mutations in the HBV genome that prevent the expression of HBeAg do not abolish the replication of HBV, indicating that this antigen is not essential for HBV...
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