Article
Characterization of novel CTNNB1 mutation in Craniopharyngioma by whole-genome sequencing.
Molecular cancer - 18 Dec 2021
He Juan, Zeng Zhen, Wang Yuelong, Deng Jiaojiao, Tang Xin, Liu Fujun, Huang Jianhan, Chen Hongxu, Liang Ruichao, Zan Xin, Liu Zhiyong, Tong Aiping, Guo Gang, Xu Jianguo, Zhu Xiaofeng, Zhou Liangxue, Peng Yong
Abstract excerpt
BACKGROUND: Craniopharyngioma (CP) is rare histologically benign but clinically challenging tumor because of its intimate relationship with the critical structure in the central brain. CP can be divided into two major histologic subtypes: adamantinomatous-type CP (ACP) and papillary-type CP (PCP). Although some genetic aberrations for both categories have been revealed in previous studies, the complete spectrum...
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