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Article

Common mutations of beta-catenin in adamantinomatous craniopharyngiomas but not in other tumours originating from the sellar region.

Acta neuropathologica - 1 Jun 2005

Buslei Rolf, Nolde Michael, Hofmann Bernd, Meissner Stephan, Eyupoglu Ilker Y, Siebzehnrübl Florian, Hahnen Eric, Kreutzer Jürgen, Fahlbusch Rudolf

Abstract excerpt

Dysregulation of the Wnt signalling pathway contributes to developmental abnormalities and carcinogenesis of solid tumours. Here, we examined beta-catenin and adenomatous polyposis coli (APC) by mutational analysis in pituitary adenomas (n=60) and a large series of craniopharyngiomas (n=41). Furthermore, the expression pattern of beta-catenin was immunohistochemically analysed in a cohort of tumours and cysts of...

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PMID: 15891929
DOI: 10.1007/s00401-005-1004-x

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APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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