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Article

Genomic Alterations of Adamantinomatous and Papillary Craniopharyngioma.

Journal of neuropathology and experimental neurology - 1 Feb 2017

Goschzik Tobias, Gessi Marco, Dreschmann Verena, Gebhardt Ursel, Wang Linghua, Yamaguchi Shigeru, Wheeler David A, Lauriola Libero, Lau Ching C, Müller Hermann L, Pietsch Torsten

Abstract excerpt

Craniopharyngiomas are rare histologically benign but clinically challenging neoplasms. To obtain further information on the molecular genetics and biology of craniopharyngiomas, we analyzed a cohort of 121 adamantinomatous and 16 papillary craniopharyngiomas (ACP, PCP). We extracted DNA from formalin-fixed paraffin-embedded tissue and determined mutational status of CTNNB1, BRAF, and DDX3X by Sanger sequencing,...

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Source

Identifiers

PMID: 28069929
DOI: 10.1093/jnen/nlw116

Genes

BRAF
CTNNB1
MIP

Variants

Provenance

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Genomic Alterations of Adamantinomatous and Papillary Craniopharyngioma.PMID 28069929Read ↗

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