Article
Craniopharyngiomas of adamantinomatous type harbor beta-catenin gene mutations.
The American journal of pathology - 1 Dec 2002
Sekine Shigeki, Shibata Tatsuhiro, Kokubu Akiko, Morishita Yukio, Noguchi Masayuki, Nakanishi Yukihiro, Sakamoto Michiie, Hirohashi Setsuo
Abstract excerpt
Craniopharyngioma is a rare tumor occurring in the sellar region comprising 3% of all intracranial tumors. To elucidate the contribution of beta-catenin gene mutation to tumorigenesis, we examined genetic alterations and expression of beta-catenin in 10 cases of adamantinomatous and 6 cases of pa...
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