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Keratin-8 null mice have different gallbladder and liver susceptibility to lithogenic diet-induced injury

23 Oct 2003

Abstract excerpt

Keratin transgenic mouse models and the association of human keratin mutations with liver disease highlight the importance of keratins in protecting the liver from environmental insults, but little is known regarding keratins and their function in the gallbladder. We characterized keratin expression pattern and filament organization in normal and keratin polypeptide-8 (K8)-null, K18-null and K19-null...

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PMID: 14576356
DOI: 10.1242/jcs.00782

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