Article
In vitro activities of garenoxacin (BMS-284756) against Haemophilus influenzae isolates with different fluoroquinolone susceptibilities.
Antimicrobial agents and chemotherapy - 1 Nov 2003
Pérez-Vázquez María, Román Federico, Aracil Belen, Cantón Rafael, Campos José
Abstract excerpt
The in vitro activity of garenoxacin (BMS-284756) against 62 clinical Haemophilus influenzae isolates with different fluoroquinolone susceptibilities was determined by the microdilution susceptibility testing method and compared with the activities of other oral quinolones and nonquinolone oral antimicrobial agents. Cefixime presented the highest intrinsic activity (MIC at which 50% of the isolates tested were...
Topics
- Amino Acid Substitution
- Anti-Infective Agents
- DNA Gyrase
- DNA Topoisomerase IV
- Fluoroquinolones
- Haemophilus Infections
- Haemophilus influenzae
- Humans
- Microbial Sensitivity Tests
- Mutation
- Quinolones
- Reverse Transcriptase Polymerase Chain Reaction