Article
Fluoxetine-induced alterations in human platelet serotonin transporter expression: serotonin transporter polymorphism effects.
Journal of psychiatry & neuroscience : JPN - 1 Sept 2006
Little Karley Y, Zhang Lian, Cook Edwin
Abstract excerpt
OBJECTIVE: Long-term antidepressant drug exposure may regulate its target molecule - the serotonin transporter (SERT). This effect could be related to an individual's genotype for an SERT promoter polymorphism (human serotonin transporter coding [5-HTTLPR]). We aimed to determine the effects of fluoxetine exposure on human platelet SERT levels. METHOD: We harvested platelet samples from 21 healthy control...
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