Article
Regulation of Kv4.3 Current by KChIP2 Splice Variants
23 Jul 2002
Abstract excerpt
BACKGROUND: The transient outward potassium current (I(to)) encoded by the Kv4 family of potassium channels is important in the repolarization of cardiac myocytes. KChIPs are a recently identified group of Ca2+-binding accessory subunits that modulate Kv4-encoded currents. KChIP2 is the only family member expressed in the heart. METHODS AND RESULTS: We previously cloned 2 novel splice variants of KChIP2 from...
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