Article
The aromatic cluster in KCHIP1b affects Kv4 inactivation gating.
The Journal of physiology - 15 Sept 2007
Van Hoorick D, Raes A, Snyders D J
Abstract excerpt
The KChIP1b splice variant has been shown to induce slow recovery from inactivation for Kv4.2 whereas KChIP1a enhanced the recovery. Both splice variants differ only by the insertion of the exon1b, rich in aromatic residues (5/11). We analysed in detail the modifications of Kv4.2 gating induced b...
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