Article
Elucidating KChIP effects on Kv4.3 inactivation and recovery kinetics with a minimal KChIP2 isoform.
The Journal of physiology - 15 Nov 2002
Patel Sangita P, Campbell Donald L, Strauss Harold C
Abstract excerpt
Kv channel interacting proteins (KChIPs) are Ca(2+)-binding proteins with four EF-hands. KChIPs modulate Kv4 channel gating by slowing inactivation kinetics and accelerating recovery kinetics. Thus, KChIPs are believed to be important regulators of Kv4 channels underlying transient outward K(+) currents in many excitable cell types. We have cloned a structurally minimal KChIP2 isoform (KChIP2d) from ferret heart....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.