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Article

EWS/FLI function varies in different cellular backgrounds.

Experimental cell research - 1 Nov 2003

Zwerner Jeffrey P, Guimbellot Jennifer, May William A

Abstract excerpt

EWS/FLI and other EWS/ets chimeric transcription factors play a central role in the biology of the Ewing family tumors. As with many oncogenes, EWS/FLI biologic activity can be demonstrated in a limited range of cellular contexts. To investigate the causes of this restriction, we demonstrate that two immortalized fibroblast lines resistant to EWS/FLI transformation, Rat1 and Yal7, express stable levels of EWS/FLI...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Oncogene Proteins, Fusion

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Source

Identifiers

PMID: 14567998
DOI: 10.1016/s0014-4827(03)00371-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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EWS/FLI function varies in different cellular backgrounds.PMID 14567998Read ↗

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