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Article

Dominant negative PDGF-C inhibits growth of Ewing family tumor cell lines.

Oncogene - 30 May 2002

Zwerner Jeffrey P, May William A

Abstract excerpt

Nearly all cases of Ewing Family Tumors (EFT) harbor chimeric EWS/ETS transcription factors which are thought to aberrantly regulate transcriptional targets of phenotypic consequence. We have recently demonstrated that EWS/ETS proteins up-regulate platelet derived growth factor-C (PDGF-C), a novel transforming growth factor. To determine if PDGF-C signaling contributes to the malignant phenotype of EFT cell...

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Identifiers

PMID: 12032822
DOI: 10.1038/sj.onc.1205486

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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