Article
Does the "hygiene hypothesis" provide an explanation for the high prevalence of multiple sclerosis in Sardinia?
Autoimmunity - 1 Aug 2003
Sotgiu Stefano, Pugliatti Maura, Sotgiu Alessandra, Sanna Alessandra, Rosati Giulio, Stefano Sotgiu, Maura Pugliatti, Alessandra Sotgiu, Alessandra Sanna, Giulio Rosati
Abstract excerpt
The "hygiene hypothesis" describes a hypothetical scenario in which the balance between TH1 (defending host against bacterial and viral infections) and TH2 (defending against parasitic infections) immune responses is pivotal and in which the consequence of reducing the infectious stressors during infancy is increased autoimmunity (TH1-mediated) and allergy (TH2-mediated). Many epidemiological observations confirm...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.