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Article

Hygiene hypothesis: innate immunity, malaria and multiple sclerosis.

Medical hypotheses - 1 Jan 2008

Sotgiu Stefano, Angius Andrea, Embry Ashton, Rosati Giulio, Musumeci Salvatore

Abstract excerpt

The establishment of new hygienic conditions plays a role in the appearance of autoimmunity in "westernalised" countries. Consistently, but still unconvincingly, several epidemiological and immunogenetic evidences link the disappearance of malaria with the increase of multiple sclerosis (MS) in Sardinia, insular Italy. To this purpose, we have made an attempt to build a relationship between malaria disappearance...

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Source

Identifiers

PMID: 17889443
DOI: 10.1016/j.mehy.2006.10.069

Genes

CHIT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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