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Article

Multiple sclerosis and anti-Plasmodium falciparum innate immune response.

Journal of neuroimmunology - 1 Apr 2007

Sotgiu Stefano, Sannella Anna R, Conti Bruno, Arru Giannina, Fois Maria Laura, Sanna Alessandra, Severini Carlo, Morale Maria Concetta, Marchetti Bianca, Rosati Giulio, Musumeci Salvatore

Abstract excerpt

Several epidemiological investigations conducted in Sardinia, insular Italy, indicate that the strong selective pressure of malaria along the centuries may have concurred to the elevated genetic MS-risk in this region. To test such hypothesis in an experimental setting, we have compared the immune response to P. falciparum (the causative agent of malaria) in Sardinian MS patients relative to their ethnic healthy...

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PMID: 17336397
DOI: 10.1016/j.jneuroim.2007.01.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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