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Article

The incidence of inhibitor development according to specific mutations--and treatment?

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jun 2003

Goodeve Anne

Abstract excerpt

The spectrum of mutations in the factor VIII (FVIII) gene was investigated in a cohort of patients with severe haemophilia A, together with the relationship between mutation type and inhibitor development DNA analysis was undertaken on 55 previously untreated patients in the Recombinate PUP mutation study who had all received the same clotting factor treatment and underwent regular monitoring for inhibitor...

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PMID: 14567530
DOI: 10.1097/00001721-200306001-00005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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