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[Linkage analysis for complex diseases: a new life for an old method].

Archives de l'Institut Pasteur de Tunis - 1 Jan 2000

Rebaï A

Abstract excerpt

In this paper, I present the main approaches used in gene mapping of complex human diseases by linkage analysis based on molecular markers. The first section describes the traditional LOD-score analysis and gives a review of different improvements and refinements of this approach, which has been proposed in order to take into account complicating factors such as incomplete penetrance, genetic heterogeneity and...

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PMID: 14658225

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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