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Article

Glutathione S-transferases (GSTT1 and GSTM1) gene deletions in Tunisians: susceptibility and prognostic implications in breast carcinoma.

British journal of cancer - 20 Oct 2003

Khedhaier A, Remadi S, Corbex M, Ahmed S B, Bouaouina N, Mestiri S, Azaiez R, Helal A N, Chouchane L

Abstract excerpt

Glutathione S-transferase Theta1 and Mu1 (GSTT1 and GSTM1) are involved in the metabolism and detoxification of a wide range of potential environmental carcinogens. Conversely, they contribute to tumour cell survival by detoxification of numerous products induced by cancer therapy. The authors designed a large study to investigate the susceptibility and prognostic implications of the GSTT1 and GSTM1 gene...

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Source

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Identifiers

PMID: 14562023
DOI: 10.1038/sj.bjc.6601292
PMCID: PMC2394332

Genes

GSTT1
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Glutathione S-transferases (GSTT1 and GSTM1) gene deletions in Tunisians: susceptibility and prognostic implications in breast carcinoma.PMID 14562023Read ↗

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Glutathione S-transferases deletions may act as prognosis and therapeutic markers in breast cancer.Semantic proximity Read ↗

Glutathione S transferase T1 gene polymorphism and its promoter methylation are associated with breast cancer susceptibility in Egyptian women.Semantic proximity Read ↗

Evaluation of molecular markers GSTM1 and GSTT1 and clinical factors in breast cancer: case-control study and literature review.Semantic proximity Read ↗

Polymorphisms of GSTM1 and GSTT1 genes in breast cancer susceptibility: a case-control study.Semantic proximity Read ↗

Detection and relevance of germline genetic polymorphisms in glutathione S-transferases (GSTs) in breast cancer patients from northern Indian population.Semantic proximity Read ↗

A functional polymorphism in the promoter region of GSTM1 implies a complex role for GSTM1 in breast cancer.Semantic proximity Read ↗

Association between polymorphisms of glutathione S-transferase genes (GSTM1, GSTP1 and GSTT1) and breast cancer risk in a sample Iranian population.Semantic proximity Read ↗

Glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) variants and breast cancer risk in Burkina Faso.Semantic proximity Read ↗

Deletion polymorphism of glutathione S-transferases M1 and T1 in the Tunisian population.Semantic proximity Read ↗

Glutathione S-transferase M1 polymorphism and breast cancer susceptibility: a meta-analysis involving 46,281 subjects.Semantic proximity Read ↗

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