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Glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) variants and breast cancer risk in Burkina Faso.

Biomolecular concepts - 9 Nov 2019

Kiendrebeogo Isabelle Touwendpoulimdé, Zoure Abdou Azaque, Sorgho Pegdwendé Abel, Yonli Albert Théophane, Djigma Florencia Wendkuuni, Ouattara Abdoul Karim, Sombie Herman Karim, Tovo Sessi Frida, Yelemkoure Edwige T, Bambara Aboubacar Hierrhum, Sawadogo Alexis Yobi, Bakri Youssef, Simpore Jacques

Abstract excerpt

Background and objective Breast cancer remains the most common cause of cancer mortality in women. The aim of this study was to investigate associations between genetic variability in GSTM1 and GSTT1 and susceptibility to breast cancer. Methods Genomic DNA was extracted from blood samples for 80 cases of histologically diagnosed breast cancer and 100 control subjects. Genotyping analyses were performed by...

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PMID: 31707358
DOI: 10.1515/bmc-2019-0020

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