Article
Evaluation of molecular markers GSTM1 and GSTT1 and clinical factors in breast cancer: case-control study and literature review.
Xenobiotica; the fate of foreign compounds in biological systems - 1 Nov 2021
Dos Santos Stéphanie Piacenti, Morissugui Sabrina Sayuri, Gimenez Martins Ana Paula D'Alarme, Fernandes Glaucia Maria de Mendonça, Russo Anelise, Galbiatti-Dias Ana Lívia Silva, Castanhole-Nunes Márcia Maria Urbanin, Francisco José Luis Esteves, Pavarino Érika Cristina, Goloni-Bertollo Eny Maria
Abstract excerpt
The study was conducted to evaluate the frequency of polymorphisms in GSTM1 and GSTT1 genes in patients with breast cancer compared with individuals without history of cancer, and the association of these polymorphisms with clinical/epidemiological parameters.There were evaluated 752 women (219 patients and 533 controls). Molecular analysis was performed by the Polymerase Chain Reaction (PCR). Statistical...
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