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Glutathione S transferase T1 gene polymorphism and its promoter methylation are associated with breast cancer susceptibility in Egyptian women.

Biotechnology and applied biochemistry - 1 Apr 2022

Raafat Nermin, Ismail Khadiga, Hawsawi Nahed M, Saber Taisir, Elsawy Wael H, Abdulmutaleb Tariq, Raafat Ahmed, Gharib Amal F

Abstract excerpt

BACKGROUND: Breast cancer (BC) is one of the leading causes of cancer mortality in women. Glutathione S-transferase (GSTT1) is involved in activation of detoxification reactions and catalysis of chemicals conjugation with glutathione. GSTT1 genotype is a limiting factor for some environmental diseases. Epigenetic changes have an essential role in BC through inappropriate interaction between genomic and...

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PMID: 33600611
DOI: 10.1002/bab.2129

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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