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Article

Estimating haplotype frequencies and standard errors for multiple single nucleotide polymorphisms.

Biostatistics (Oxford, England) - 1 Oct 2003

Li Shuying Sue, Khalid Najma, Carlson Christopher, Zhao Lue Ping

Abstract excerpt

Estimating haplotype frequencies becomes increasingly important in the mapping of complex disease genes, as millions of single nucleotide polymorphisms (SNPs) are being identified and genotyped. When genotypes at multiple SNP loci are gathered from unrelated individuals, haplotype frequencies can be accurately estimated using expectation-maximization (EM) algorithms (Excoffier and Slatkin, 1995; Hawley and Kidd,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 14557108
DOI: 10.1093/biostatistics/4.4.513

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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